Enzymes are proteins catalyzing virtually any reaction going on in living organisms, with incomparable specificity and efficiency. Some enzymes turn food into nutrients, while others contribute to the production of energy or cellular components. Other enzymes are involved in host defense, communication, or reproduction.
Previously the predominant thinking in the industry was that it is necessary to eradicate as many bacteria as possible to heal dermal and dental issues. However today we understand that it is important to maintain a healthy microbiome.
The total oral health market for dogs consists of three sectors:
Non-Biocidal Biofilm Disruption
Biocidal Biofilm Disruption
5 % Non-Biocidal Biofilm Disruption (Kalzyme): A new and innovative class of products that use a mode of action associated with creating a protective barrier that prevents biofilm formation or uses a mechanism to disrupt existing Biofilm. These product preserve a healthy Microbiome.
30 % Biocidal Biofilm Disruption A substance intended to destroy, deter, render harmless and prevent the action of or exert a controlling effect on any harmful organism by any means other than mere physical or mechanical action. Can be harsh, synthetic chemicals.
65 % Mechanical Action Mechanical disruption of the plaque layer on the tooth surface. However, these products can fail to address underlying bacterial issues, inflammation of the gums, gingivitis, periodontal disease, and bad breath.
Bulk chemicals are predominately used in oral health care. Most bulk chemicals are highly effective against bacteria and even other pathogens but may cause severe side effects, especially on long term use as intended in preventive health care.
The same is true also for pH adjusting products. The side effects may not be seen as severe, but they do have a negative effect on the microbiome. This in turn may have consequent negative health effects, including damaging effects on vital organs such as the brain and the heart.
Enzymes solutions may be seen as a paradigm shift in dermal and dental health care as enzyme products use nature’s own tools to promote dental and dermal health. One type of enzyme products uses enzymes for the production of bactericidal chemicals, which are similar to the bulk chemicals mentioned above. The other type prevents attachment of bacteria through hydrolytic action. Further additives may be added to prevent adhesion.